Prosthetic joint infections (PJI) occurs in approximately 1% to 2 % of all
primary total hip and knee arthroplasties. Given the increasing number of total joints performed throughout the United States,
total hip and knee infections create a significant burden on the health care system. The cost of treating PJI in the United
States alone is approximately $200 million per year.
An Ortho-tag can
also host multiple nanosensors to monitor the biological environment around an implant. Ortho-tag biosensors can assist in
non-invasively detecting (in real-time) post-operative prosthetic infections by measuring changes in tissue temperature, pH,
and other indicating biomarkers, including, in the future, the identification of specific microorganisms.
This product has not
yet been cleared for sale in the United States by the FDA